US AI startups (2025) with $100M+ funding

Several U.S.-based AI startups secured mega-rounds ($100M+) in funding in the first half of 2025. Below is a month-by-month summary of each company, its focus, and the details of its funding round, with sources for verification.

January 2025

• ElevenLabs (AI voice tech): Raised a $250 million Series C led by ICONIQ Growth in Jan 2025, at a post-money valuation above $3 billion. The New York startup offers advanced text-to-speech and voice-cloning AI tools, and its products are used by many content creators and media companies (customers include The Washington Post, HarperCollins, etc.).
• Hippocratic AI (healthcare AI): Raised $141 million Series B led by Kleiner Perkins on Jan 9, 2025, valuing the company at about $1.64 billion. Hippocratic AI is developing a healthcare-specific large language model and AI agents to help medical staff, aiming to address nursing shortages by automating low-risk clinical tasks.

February 2025

• Together AI (AI cloud platform): Announced a $305 million Series B (Feb 20, 2025) co-led by General Catalyst and Prosperity7, valuing the company around $3.3 billion. Together AI provides a cloud platform optimized for open-source AI models (serving 450K+ developers), including tools for inference and training (e.g., hosting Meta’s Llama and other models).
  
• Lambda (AI hardware/cloud): Raised $480 million Series D on Feb 19, 2025, co-led by Andra Capital and SGW. Lambda supplies GPU-based cloud services and workstations for AI developers. The new funding will expand its Lambda Cloud platform and tools (e.g. Lambda Chat hosting open models) with more NVIDIA GPUs.
  
• Abridge (healthcare AI): Announced a $250 million Series D on Feb 17, 2025, co-led by Elad Gil and IVP. Abridge offers an AI platform that automatically transcribes and summarizes doctor-patient conversations. It is now deployed in over 100 major health systems (e.g. Duke, Johns Hopkins, Mayo Clinic) and will use the funding to scale its clinical conversational AI and reasoning engine.
  
• Eudia (legal AI): Raised $105 million Series A led by General Catalyst on Feb 13, 2025. Eudia provides AI “legal agents” to augment corporate legal teams (e.g. in-house counsel). The startup enables automation of legal workflows via specialized LLM-based agents for routine legal tasks, aiming to let lawyers focus on strategy rather than paperwork.
  
• EnCharge AI (AI chip startup): Secured just over $100 million in a Series B (reported Feb 13, 2025), led by Tiger Global. EnCharge AI, spun out of Princeton, designs analog memory chips and accelerators for on-device AI. Its low-power, analog chip technology (to be embedded in devices like laptops and phones) aims to speed up AI inference and greatly reduce energy use.
  
• Harvey (legal AI): Raised $300 million Series D led by Sequoia on Feb 12, 2025. Harvey builds AI-powered tools for law firms and corporate legal departments (e.g., AI assistants for drafting documents). The round, which also included Kleiner Perkins, OpenAI’s Startup Fund, and others, valued the 3-year-old company at about $3 billion. Harvey saw 4× revenue growth in 2024 and will use the funds to expand its AI-driven legal platform and enterprise products.

March 2025

• OpenAI (LLM/chatbot maker): Announced a historic $40 billion private funding round (closed Mar 31, 2025) led by SoftBank, valuing the company at $300 billion post-money. Existing investors Microsoft, Thrive Capital, Coatue, and others also participated. OpenAI will use a large portion (roughly $18B) to build out its U.S. “Stargate” AI data center infrastructure.
  
• Nexthop AI (AI networking): Launched with a $110 million Series A on Mar 25, 2025 (led by Lightspeed Venture Partners). Nexthop builds high-performance networking hardware and software for hyperscale AI data centers. Its custom networking solutions aim to help cloud providers and AI companies handle the enormous scale and power requirements of modern AI clusters.
• Insilico Medicine (AI drug discovery): Raised $110 million Series E on Mar 13, 2025 (co-led by Value Partners Group and Pudong CTT). Insilico is a biotech startup using generative AI (its Pharma.AI platform) to accelerate drug discovery. The round, which brought Insilico to a $1 billion valuation, will fund advancement of its drug pipeline (including a lead candidate for pulmonary fibrosis) and further development of its AI research platform.
  
• Celestial AI (AI hardware photonics): Announced a $250 million Series C1 on Mar 11, 2025, led by Fidelity (with participation from BlackRock, Tiger Global, etc.). Celestial AI develops “Photonic Fabric” optical interconnect technology for AI data centers. Its technology uses silicon photonics to connect chips and memory at high bandwidth/low latency, aiming to improve the performance and energy efficiency of large-scale AI clusters.
  
• Lila Sciences (AI science platform): Flagship Pioneering announced on Mar 10, 2025 that it had raised $200 million in seed funding to launch Lila Sciences. Lila is building an AI-driven “scientific superintelligence” platform with fully autonomous labs, to accelerate research across life sciences, chemistry, materials science, etc. The funds will develop its AI models and lab automation infrastructure for rapid scientific discovery.
  
• Reflection AI (autonomous coding): Emerged from stealth with a $130 million total seed+Series A raise (announced Mar 7, 2025). Founded by ex-Google DeepMind researchers, Reflection AI is developing fully autonomous AI coding agents (beyond co-pilots) that can write, test, and deploy code end-to-end. The company reported $130M raised – a $25M seed (led by Sequoia/CRV) plus a $105M Series A (led by Lightspeed/CRV) with plans to scale its team globally (SF, NYC, London, Paris) and pursue its vision of “superintelligent” coding systems.
  
• Turing (AI workforce platform): Raised $111 million Series E on Mar 6, 2025 (led by Khazanah Nasional). Turing connects companies with a large global pool of vetted engineers to work on AI and software projects. It powers teams building LLMs and AI applications (including partnering on OpenAI model development) and has grown to ~$300 M ARR. The new funding (double its prior valuation) will help Turing expand into new markets and use cases.
  
• Shield AI (defense drones): Raised $240 million Series F on Mar 6, 2025 (co-led by L3Harris and Hanwha) at a $5.3 billion valuation. Shield AI builds autonomous AI systems for defense, such as “Hivemind” software that enables drones and fighter jets to operate autonomously. The latest round (also backed by Andreessen Horowitz, the US Innovative Tech Fund, etc.) will help commercialize its AI-powered drone tech for broader markets beyond the military.
  
• Anthropic (LLM company): Raised $3.5 billion Series E on Mar 3, 2025, led by Lightspeed. This massive round (including Salesforce Ventures, Menlo Ventures, etc.) values Anthropic at about $61.5 billion post-money. Anthropic develops AI models like Claude and focuses on AI safety and alignment. It will use the funds to scale compute, advance research (e.g. on interpretability), and global expansion of its next-gen AI systems.

April 2025

• SandboxAQ (AI + quantum): Closed over $450 million Series E on Apr 4, 2025 (with new investors including Ray Dalio, Google, Nvidia). Spun out of Google’s quantum/AI group, SandboxAQ builds AI and quantum computing platforms for enterprise use (such as Large Quantitative Models for drug discovery, chemistry, finance). With ~$950M raised to date, it will use the new capital to advance its AI-driven quantitative models in industries like life sciences and cybersecurity.
• Runway (AI media tools): Raised $308 million Series D on Apr 3, 2025 (led by General Atlantic), valuing the startup at over $3 billion. Runway provides generative AI models and tools for media and video production (e.g. its Gen-4 video model). The funding will fuel its media AI research and the expansion of Runway Studios for film/animation production. Investors include SoftBank, Nvidia, Fidelity, etc.

May 2025

• Snorkel AI (AI data platform): Raised $100 million Series D on May 29, 2025 (led by Addition) at a $1.3 billion valuation. Snorkel AI offers a programmatic data platform for labeling and tuning AI models. Its new products (Snorkel Evaluate and Expert Data-as-a-Service) help enterprises create specialized datasets and evaluation metrics. The funding will expand its research on domain-specific data for reliable AI deployment.
  
• LM Arena (AI benchmarking): Raised $100 million seed on May 21, 2025 (co-led by a16z and UC Investments) at a $600 million valuation. LM Arena operates a crowdsourced platform for AI model benchmarking and leaderboards, used by AI labs like OpenAI, Google, and Anthropic. The funds will support its mission of providing reliable, community-driven AI model evaluations and “responsible AI” research.
  
• TensorWave (AI infrastructure): Raised $100 million Series A on May 14, 2025 (co-led by Magnetar and AMD Ventures). TensorWave is building large data centers equipped primarily with AMD hardware (e.g. thousands of AMD Instinct GPUs) to offer cloud services optimized for AI training. With $146.7M total raised, it is deploying 8,192 AMD GPUs and aims to provide lower-cost AI compute by eschewing Nvidia in favor of AMD.

June 2025

• Glean (enterprise AI search): Raised $150 million Series F on June 10, 2025 (led by Wellington, with Sequoia, Lightspeed, etc.), at about a $7.2 billion valuation. Glean provides an AI-powered search engine for companies’ internal knowledge, using LLMs to let employees search across documents, chats, and data. The new funding will scale its enterprise search tools that help employees find information quickly in large organizations.
• Anysphere (AI coding assistants): Raised $900 million Series C on June 5, 2025 (led by Thrive Capital) at a ~$9.9 billion valuation. Anysphere makes Cursor, an AI coding assistant for developers. It has rapidly grown to over $500M ARR and doubled revenue every two months. The funding (Sources say it was first reported by Bloomberg) will help Anysphere scale Cursor’s development of “vibe coder” tools for coding and enterprise software generation.

Each of the above funding announcements is documented by TechCrunch or official press releases, ensuring the accuracy of these figures and details. These rounds reflect the continuing surge in AI investment through early 2025, with startups across diverse domains (from data infrastructure and hardware to specialized AI software) achieving “mega-round” status.